Best Cleaner For Pet Stains in 2022 [*Top Picks*]

Looking for the best cleaner for pet stains on the market? We’ve got you covered. Check out our ratings of absolute bestsellers below and make a final decision.

6298 Reviews Scanned

  • Resolve Ultra Pet Stain & Odor Remover Spray, 32oz
    Bestseller #1
    Resolve Ultra Pet Stain & Odor Remover Spray, 32oz (386)
      Eliminates pet odors with Odor Stop Technology Freshens with a light, clean scent Discourages pet resoiling Removes tough pet stains like urine, vomit, and feces from rugs and carpets also works great on everyday stains like red wine, grape juice, and greasy food
  • Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for Home - Carpet Stain Remover for Cats and Dog Pee - Enzymatic Cat Urine Destroyer - Carpet Cleaner Spray
    Bestseller #1
    Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for Home - Carpet Stain Remover for Cats and Dog Pee - Enzymatic Cat Urine Destroyer - Carpet Cleaner Spray (3003)
      CERTIFIED GENTLE AND SAFE Chlorine free and color safe. Safe to use around pets and children. No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (CRI) ELIMINATES STAINS, ODORS AND RESIDUE If it’s gross, it’s gone. Not just the stain, but the stink. From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all. EVERY SURFACE, EVERY TIME For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen. ENZYME ACTIVATED The key is getting to the problem deep-down. This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated. 100% SATISFACTION GUARANTEED An Amazon best seller—for a reason. If your stains and odors aren’t gone, neither is your money. We’ll refund it in full.
  • Woolite Advanced Pet Stain & Odor Remover + Sanitize, 2618, 22oz (Pack of 2)
    Bestseller #1
    Woolite Advanced Pet Stain & Odor Remover + Sanitize, 2618, 22oz (Pack of 2) (386)
      Kills 99. 9% of bacteria on soft surfaces (Kills 99. 9% of Enterobacter aerogenes (ATCC 13408) and Staphylococcus aureus (ATCC 6538)) Permanently removes tough pet stains. Penetrates to eliminate pet odors at their source. Cleans, sanitizes, and deodorizes in one easy step. Leaves carpets sanitized for children and pets when used as directed. BONUS Stomp 'n Go Pet Stain Lifting Pad instantly removes tough stains including blood, feces, grease, oil, urine, and vomit. Sprayer color may vary.
  • Bissell SpotClean ProHeat Portable Spot and Stain Carpet Cleaner, 2694, Blue
    Bestseller #1
    Bissell SpotClean ProHeat Portable Spot and Stain Carpet Cleaner, 2694, Blue (386)
      Tank capacity 37 ounce; Heatwave technology maintains consistent water temperature while cleaning 3 inch tough stain tool for cleaning stairs, upholstery and hard to reach places Deep reach tool removes embedded dirt and stains from the bottom up; Dirt tank capacity Self cleaning tool makes cleaning out the machine a breeze Removable water tanks for easy filling and emptying
  • BISSELL SpotClean Pet Pro Portable Carpet Cleaner, 2458
    Bestseller #1
    BISSELL SpotClean Pet Pro Portable Carpet Cleaner, 2458 (73)
      Every Bissell purchase helps save pets. Bissell proudly supports Bissell pet foundation and its mission to help save homeless pets. Our most powerful portable spot and stain cleaner for carpets, stairs, upholstery, auto interiors, and more. Combines superior suction, scrubbing action and professional cleaning solution to remove stubborn pet stains, embedded dirt and more. Provides a deep clean that leaves you with professional-style results. Permanently removes tough pet stains with the power of OXY. Includes a stain trapper tool to catch the dirtiest pet messes. Also comes with a 3" tough stain tool and two trial-size pet pro oxy urine eliminator formulas.
  • Bissell 74R7 Pet Stain & Odor Portable Machine Formula, 32-Ounce, Fl Oz
    Bestseller #1
    Bissell 74R7 Pet Stain & Odor Portable Machine Formula, 32-Ounce, Fl Oz (386)
      Every BISSELL purchase helps save pets. BISSELL proudly supports BISSELL Pet Foundation and its mission to help save homeless pets. Removes tough pet stains and messes. Eliminates difficult pet odors. Quick and effective spot cleaning on carpet, area rugs and upholstery. Great for removing tough pet stains like urine, vomit, blood, and tracked-in dirt. Formula made for portable carpet cleaners. Contains no heavy metals, phosphates or dyes. Biodegradable Detergents. Pet and family safe when used as directed.
  • BISSELL® PET PRO OXY Spot & Stain Formula for Portable Carpet Cleaners, 32 oz, 2034
    Bestseller #1
    BISSELL® PET PRO OXY Spot & Stain Formula for Portable Carpet Cleaners, 32 oz, 2034 (386)
      Every Purchase Saves Pets. BISSELL proudly supports BISSELL Pet Foundation and its mission to help save homeless pets. Permanently Remove Tough Pet Stains. Works on urine, feces, vomit, tracked-in dirt, and blood. Eliminates Tough Pet Odors. Leaves a fresh scent. Pet & Family Safe When Used as Directed. Formulated for Portable Carpet Cleaners. Effectively deep clean spots and stains in high-traffic areas and carpeted stairs, and refreshes upholstery. Earth friendly formula. Biodegradable detergents. Contains no heavy metals, phosphates or dyes. *Packaging may vary.
  • Angry Orange Enzyme Cleaner & Pet Stain Remover Spray - 32oz Pet Odor Eliminator for Home, Carpet, and Floor - Cat and Dog Urine Destroyer (Fresh Citrus Scent) 
    Bestseller #1
    Angry Orange Enzyme Cleaner & Pet Stain Remover Spray - 32oz Pet Odor Eliminator for Home, Carpet, and Floor - Cat and Dog Urine Destroyer (Fresh Citrus Scent)  (12898)
      Enjoy all the furry love without the nasty messes! Our enzyme-active pet stain and odor remover can tackle any stubborn stains and foul smells, including pet urine, feces, and even vomit. This isn't just another pet spray that masks the bad odors and stains. Our floor & carpet odor eliminator destroys them with enzymes that activate upon contact and ensure 80 hours of freshness. Discover an enzyme cleaner that can clean it all! Our solution is a pet cleaner for carpet, hardwood floors, tile, litter boxes, pillows, kennels, and more. Made with enzymes and natural ingredients, this odor & urine remover for dogs and cats will leave a subtle orange scent behind without the use of harsh ingredients. We care about making a great enzymatic cleaner with the strength to destroy messes, and keeping you and your pets happy. If you have any questions or concerns, our customer support is available 24/7.
  • Bissell Pet Stain Eraser PowerBrush, 2837
    Bestseller #1
    Bissell Pet Stain Eraser PowerBrush, 2837 (386)
      Every Purchase Saves Pets. BISSELL proudly supports BISSELL Pet Foundation and its mission to help save homeless pets. Rotating DirtLifter PowerBrush. Our only portable carpet cleaner with a rotating brush to power through tough spots and stains with minimal effort. Grab & Go Convenience. Cordless machine includes a lithium-ion battery with extended run time. Power Rating: 7.2 V OXY Formula included. Instantly remove tough pet messes, embedded dirt, spills, and more. Ready-to-Use Formula. No mixing with water required, plus formula can be stored in the machine, so it's already ready to clean when needed. BONUS Stationary Pet Tool made to tackle tough pet messes.
  • Simple Solution Cat Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 32 Ounces
    Bestseller #1
    Simple Solution Cat Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 32 Ounces (386)
      DESIGNED FOR THE TOUGHEST ODORS AND ORGANIC STAINS- Simple Solution pet Extreme Stain and Odor remover is three times stonger than our regular formula to eliminate tough dog and cat odors and stains. PROFESSIONAL STRENGTH FORMULA - Extreme Stain and Odor Remover is a professional strength Pro-Bacteria and enzyme formula that breaks down and eliminates stains and odors. SPECIFICALLY FOR PET ODORS AND ORGANIC STAINS - Safely and quickly removes dog and cat urine, feces, and vomit on carpet, upholstery, bedding, fabric toys, clothing, or other water-safe surfaces in your home NEW PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozle sprayer (foam, mist, and stream).
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